Topic by Driver

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Anyone have any experience with taking Chantix(Varenicline) orZyban(bupropion) to quit smoking?
From what I've read it seems Zyban works better and Chantix is a fairly new drug for it.Varenicline is a partial antagonist of the niACH receptor and Bupropion is an antidepressant that acts as a dopamine reuptake inhibitor, and nicotinic antagonist. Sounds similar in that they dumb/prevent the pleasure of smoking. Seems to me thought that the Bupr. sounds like it would work better since Varen. is only a partial nicotinic antagonist plus Bupr. being an antidepressent helps with the depressive moods associated with quitting.

So the Question: Anyone had experience with both or either or knew someone that has stories about it? Whats prescribed commonly? What side effects and or pros and cons for each did you experience?
Isnt a full nicotinic antagonist better than a partial? And why did they leave out the dopamine reuptake inhibitor?

I will try web-md on this too. Thanks

  Reply by Kim

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Quit Smoking Pill... Chantix(Varenicline) or Zyban(bupropion)

I am not a big fan of taking drugs to stop the addiction to another drug. If you really want to quit smoking the program on this site really works and it does not rely on patches or gum or pills.

http://uhelpyourself.com/quitsmoke

Check it out and good luck quitting.

Tom

  Reply by abelincon

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Quit Smoking Pill... Chantix(Varenicline) or Zyban(bupropion)

My sister in law took Chantix for about three months and she smoked for 25 years. She quit. My brother took Zyban and it did not work for him. I know that Chantix is fairly new on the market, but as a nurse the doctors are using it more than Zyban.

  Reply by Drunk

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Quit Smoking Pill... Chantix(Varenicline) or Zyban(bupropion)

I am not a smoker, so have not tried either personally, but patients I have seen who REALLY want to quit have had better luck with Chantix. It blocks that addiction area in the brain, supposedly.

The main side effect is nausea, & if u experience that, u can stay at the lower dose until ur body gets used to it.

Good luck with quitting. I took care of several patients today who r long term smokers. We cut off a leg with dead, black toes (like this: http://medicine.ucsd.edu/clinicalmed/extremities-toe-gangrene2.jpg)
caused by vascular insufficiency on one, & fixed a carotid artery on another. Cigarettes r murder on our blood vessels. Quitting now can save u a LOT of trouble later on. Do whatever it takes to be successful!

  Reply by Gadget

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Quit Smoking Pill... Chantix(Varenicline) or Zyban(bupropion)

I do not believe in any of the drugs on the market to quit smoking primarily because I have seen so many people use them just to start up smoking again heavier. I was a heavy smoker for 23 years, (60+ per day) & quit smoking using will power. I convinced myself every time I lit a smoke it tasted horrible & would put the smoke out & would not light another until that was finished. Consequently one cigarette waited a week to be lit a 3rd time & the rest is history. It all boils down to the fact that if u really want to give up smoking u will, otherwise stop trying

  Reply by dwi

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Quit Smoking Pill... Chantix(Varenicline) or Zyban(bupropion)

I tried Chantix. It did absolutely nothing for me. I still had huge cravings for cigarettes. Therefore, I am still a smoker.